Algunas personas que padecen leucemia mieloide aguda (AML) tienen uno o más de los factores de riesgo conocidos (consulte la sección. Gracias a los avances en los tratamientos y los ensayos clínicos, las perspectivas para los niños con leucemia mieloide aguda son esperanzadoras. Tratamiento de la leucemia promielocítica aguda. .. acute promyelocytic leukemia (M3) developing into an M3 acute myelocytic leukemia without PML/ RARa.
|Published (Last):||14 December 2008|
|PDF File Size:||15.57 Mb|
|ePub File Size:||18.39 Mb|
|Price:||Free* [*Free Regsitration Required]|
Acute promyelocytic leukemia as a paradigm for targeted therapy. More on geographic hematology: Brit J Haematol ; Suppl.
Association between increased body mass index and a diagnosis of acute promyelocytic leukemia in patients with acute myeloid leukemia. Treatment of acute promyelocytic leukemia: Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia.
Leucemia mieloide aguda
Principles, applications and problems. In addition, we elected to deliver ATRA fully on an outpatient basis, thus diminishing hospitalization costs. High frequency of acute promyelocytic leukemia among latinos with acute myeloid leukemia Letter.
Oral prednisone is used prophylactically, ATRA is given on an outpatient basis and adriamycin is used instead of other anthracyclines. J Am Stat Assoc ; leuceia ATRA was given until reaching a complete hematological remission, as defined by usual criteria.
A single institution experience. Three patients received an autologous peripheral blood stem cell transplantation 4, 6, 9,19 after achieving the molecular remission, in two instances during the first CR and in one, during the second CR vide supra.
Promyelocytic leukemia in Mexican mestizos. Results from several randomized studies have evaluated various regimens of ATRA alone or in combination with CT to determine optimal induction therapy in patients with newly diagnosed APL.
From genetics to treatment.
¿Sabemos qué causa la leucemia mieloide aguda?
High frequency of acute promyelocytic leukemia in Mexican mestizos. Acta Haematol ; Blood ; 84 Suppl. Outpatient supportive therapy after induction to remission therapy in adult acute myelogenous leukaemia AML is feasible: Fourteen patients were followed for more than 30 days and therefore, prospectively accrued in this study; they were observed for periods ranging from 67 to 4, days median 1, All transretinoic acid ATRA.
Substantial progress has occurred in the treatment of APL because of improved understanding of the pathophysiology of the disease and identification of a molecular target. Aceptado el 6 de abril de The method which we have previously published and employed to treat patients with PML, 13 includes prednisone during the first three weeks of treatment; this addition has resulted in the eradication of the ATRA syndrome, which in our hands is no longer a problem; prospective studies to define the definite role of steroids in this setting are needed.
High frequency of acute promyelocyitic leukemia in Mexican Mestizos. Recibido el 4 de noviembre de Medicin Univ ; 1: Kaplan EL, Meier P. Correspondence and reprint request: Vasco de Quiroga No. Ann Biol Clin ; Nonparametric estimations from incomplete observations. Cellular immunophenotypes in 97 adults with acute leukemia. Clin Lab Haematol ; The molecular remission was achieved after the administration of ATRA in five patients, whereas in the remaining eight, chemotherapy CT was required to finally achieve it.
The treatment employed differs from others in: Cytometry Communications in Clinical Cytometry ; Leuk Lymphoma ; Flow cytometry in the clinical laboratory. Toxicity and survival in de novo patients.
Semin Hematol ; There were no instances of the ATRA syndrome. Blood ; 90 Suppl. Pathogenesis and management of acute promyelocytic leukemia. Eur J Haematol ; Report of the first Latin American consensus conference for flow cytometric immunophenotyping of promielofitica. The roles of both consolidation therapy with CT including anthracyclines as well as the maintenance therapy with ATRA, mercaptopurine and methotrexate have been also well defined.
Am J Hematol ; Annu Rev Med ;